Pancreatic Plasmacytoma Misdiagnosed as Neuroendocrine Tumour: A Pathologist’s Dilemma
Published: February 1, 2020 | DOI: https://doi.org/10.7860/JCDR/2020/43083.13534
Sakthisankari Shanmugasundaram, Umamaheswari Gurusamy, Prasanna N Kumar, Biku Joseph John
1. Assistant Professor, Department of Pathology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
2. Associate Professor, Department of Pathology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
3. Professor, Department of Pathology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
4. Professor, Department of Hepatobiliary and Pancreatic Surgery, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
Correspondence
Dr. Sakthisankari Shanmugasundaram,
Peelamedu, Coimbatore, Tamil Nadu, India.
E-mail: sakthissankari@gmail.com
Extramedullary plasmacytomas are rare, constituting to about 5% of plasma cell neoplasms. Pancreatic involvement is uncommon constituting to about 2.3%. Localised solitary plasmacytomas has a good response to radiation. When they are associated with pre-existing multiple myeloma, their prognosis is poor. A case of plasmacytoma of pancreas presenting with obstructive jaundice preceding plasma cell leukaemia is presented here. The lesion was misdiagnosed by fine needle aspiration cytology as neuroendocrine neoplasm. The patient did not present with symptoms of myeloma initially. The present case highlights the significance of considering other causes of pancreatic mass than primary carcinomas.
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